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Genedata

Genedata
TypePrivate
IndustryBioinformatics
Founded1997
HeadquartersBasel, Switzerland
Key peopleOthmar Pfannes CEO
ProductsSee detailed listing
Employees120+
Websitewww.genedata.com

Genedata is a bioinformatics solution provider based in Basel, Switzerland. It provides products to the Pharmaceutical industry, Biotechnology, Agriculture and Academia worldwide. Genedata has received considerable positive attention in several independent industry publications such as GenomeWeb,[1] BioInform, and Bio-IT World.[2]

As Member of the InnoMed PredTox research consortium Genedata is collaborating with major European pharma companies on the application of toxicogenomics in pharmaceutical development processes.[3]

Contents

Products

  • Genedata Phylosopher - Target-centric research information management
  • Genedata Screener - Enterprise solution for High-throughput[4][5] and High-content Screening[6] data management and analysis
  • Genedata Expressionist - Biomarker discovery platform that integrates and analyzes gene expression[7]

,[8][9][10][11][12][13][14][15][16][17][18][19][20][21] proteomics,[22][23] metabolomics, as well as projects spanning across different technology domains ("cross-omics") like in toxicogenomics[24]

  • Genedata Analyst - Software solution for the integration and interpretation of experimental data in the life science R&D
  • Genedata Selector - Data analysis and management system that supports strain optimization for industrial microorganisms
  • Genedata Biologics - Data analysis and management platform that supports Biologics R&D operations

External links

See also

  • Bioinformatics companies
  • toxicogenomics

References

  1. ^ http://www.google.com/search?hl=en&am p;as_q=site%3Awww.genomeweb.com+%22ge nedata%22&as_epq=&as_oq=& as_eq=&num=10&lr=&as_file type=&ft=i&as_sitesearch=& ;as_qdr=all&as_rights=&as_occt=any&cr=&as_nlo=&as_nhi=&safe=images
  2. ^ Bio-IT World
  3. ^ Gallagher, WM; Tweats, Koenig (2009). "Omic profiling for drug safety assessment: current trends and public-private partnerships". Drug Discovery Today 14 (7–8): 337–42. doi:10.1016/j.drudis.2009.02.001. PMID 19340928. 
  4. ^ Liming Chang Milbauer, Peng Wei, Judy Enenstein, Aixiang Jiang, Cheryl A. Hillery, J. Paul Scott, Stephen C. Nelson, Vidya Bodempudi, James N. Topper, Ruey-Bing Yang, Betsy Hirsch, Wei Pan, and Robert P. Hebbel, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings Genetic endothelial systems biology of sickle stroke risk", Blood. 2008; 111:3872-3879
  5. ^ Zhijin Wu, Dongmei Liu, and Yunxia Sui, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings", J Biomol Screen. 2008; 13:159-167
  6. ^ Duerr et al. "Robust hit identification by quality assurance and multivariate data analysis of a high-content, cell-based assay", J Biomol Screen. 2007 Dec;12(8):1042-9 [1]
  7. ^ Nadine Zidek, Juergen Hellmann, Peter-Juergen Kramer, and Philip G. Hewitt, "Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays", Toxicol. Sci. 2007; 99(1): p. 289-302
  8. ^ Walter Lucchesi, Gareth Brady, Oliver Dittrich-Breiholz, Michael Kracht, Rainer Russ, and Paul J. Farrell, "Differential gene regulation by Epstein-Barr virus Type 1 and Type 2 EBNA2",J Virol. 2008 May 14
  9. ^ Ramiro Dip, Sarah Lenz, Jean-Philippe Antignac, Bruno Le Bizec, Hans Gmuender, and Hanspeter Naegeli, "Global gene expression profiles induced by phytoestrogens in human breast cancer cells",Endocr. Relat. Cancer. 2008; 15:161-173
  10. ^ Andrea J. O'Hara, Wolfgang Vahrson, and Dirk P. Dittmer, "Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma",Blood. 2008; 111:2347-2353
  11. ^ Benita K.T. Tan, Lay Keng Tan, Kun Yu, Puay Hoon Tan, Ming Lee, Lang Hiong Sii, Chow Yin Wong, Gay Hui Ho, Allen W.Y. Yeo, Pierce K.H. Chow, Heng Nung Koong, Wei Sean Yong, Dennis T.H. Lim, London L.P.J. Ooi, Khee Chee Soo, and Patrick Tan, "Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer",Clin. Cancer Res. 2008; 14:461-469
  12. ^ Suk Mei Wang, London Lucien P.J. Ooi, and Kam M. Hui, "Identification and Validation of a Novel Gene Signature Associated with the Recurrence of Human Hepatocellular Carcinoma", Clin. Cancer Res., Nov 2007; 13: 6275 - 6283
  13. ^ Siew Leng Tai, Pascale Daran-Lapujade, Michael C. Walsh, Jack T. Pronk, and Jean-Marc Daran, "Acclimation of Saccharomyces cerevisiae to Low Temperature: A Chemostat-based Transcriptome Analysis", Mol. Biol. Cell, Oct 2007; 10.1091/mbc.E07-02-0131
  14. ^ Carsten Lange, Diane Starrett, Julia Goetsch, Volker Gerke, and Ursula Rescher, "Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25", J. Leukoc. Biol. published 12 September 2007, 10.1189/jlb.0307158
  15. ^ Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Jul 2007; 77: 165 - 171
  16. ^ Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, and Brian G. Van Ness, "A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma", Cancer Res., May 2007; 67: 4069 - 4078
  17. ^ Kerstin Stemmer, Heidrun Ellinger-Ziegelbauer, Hans-Juergen Ahr, and Daniel R. Dietrich, "Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis", Cancer Res., May 2007; 67: 4052 - 4068
  18. ^ Jeffrey D. Lande, Jagadish Patil, Na Li, Todd R. Berryman, Richard A. King, and Marshall I. Hertz, "Novel Insights into Lung Transplant Rejection by Microarray Analysis", Proceedings of the ATS, Jan 2007; 4: 44 - 51
  19. ^ Thorsten Müller, Caoimhin G. Concannon, Manus W. Ward, Ciara M. Walsh, Anca L. Tirniceriu, Florian Tribl, Donat Kögel, Jochen H.M. Prehn, and Rupert Egensperger, "Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD)", Mol. Biol. Cell, Jan 2007; 18: 201 - 210
  20. ^ Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Mar 2007; 10.1095/biolreprod.106.059493
  21. ^ Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler, "The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1alpha", J. Immunol., Mar 2007; 178: 3198 - 3207
  22. ^ Sebastian Wiese, Thomas Gronemeyer, Rob Ofman, Markus Kunze, Claudia P. Grou, Jose A. Almeida, Martin Eisenacher, Christian Stephan, Heiko Hayen, Lukas Schollenberger, Thomas Korosec, Hans R. Waterham, Wolfgang Schliebs, Ralf Erdmann, Johannes Berger, Helmut E. Meyer, Wilhelm Just, Jorge E. Azevedo, Ronald J. A. Wanders, and Bettina Warscheid, "Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling", Mol. Cell. Proteomics. published 2 September 2007, 10.1074/mcp.M700169-MCP200
  23. ^ Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, and Setsuo Hirohashi, "Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma", Mol. Cell. Clin. Cancer Res., Feb 2007; 13: 799 - 805
  24. ^ Heidrun Ellinger-Ziegelbauer, Hans Gmuender, Arnd Brandenburg, Hans Juergen Ahr, "Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies", Mutation Research 637 2007 23-39
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