Faktor komplemen D

Faktor komplemen D disebut juga faktor D (bahasa Inggris: complement factor D, factor D, adipsin, C3 convertase activator, properdin factor D) adalah protein dari golongan tripsin peptidase yang dikodikasi pada gen CFD[1] atau DF atau PFD.

Faktor D juga merupakan serina protease yang disekresi oleh sel adiposit ke dalam sirkulasi darah sebagai stimulasi transportasi glukosa untuk akumulasi trigliserida di dalam adiposit dan menghambat lipolisis.[2]

Ekspresi lipid pada faktor D membuat para ahli beranggapan bahwa jaringan adiposa juga turut berperan dalam sistem kekebalan.[1] Faktor D berperan dalam lintasan kekebalan alternatif pada sistem kekebalan dengan mengiris faktor B, dan menekan zat antigenik yang disekresi oleh patogen

Rujukan

  1. ^ a b "Entrez Gene: CFD". 
  2. ^ Ronti T, Lupattelli G, Mannarino E (April 2006). "The endocrine function of adipose tissue: an update". Clin. Endocrinol. (Oxf) 64 (4): 355–65. doi:10.1111/j.1365-2265.2006.02474.x. PMID 16584505. Ringkasan – medscape.com. 

Pranala luar

 
Zimogen
Angiotensinogen " Caspase " F12 " Kimotiypsinogen " Pepsinogen " Proelastase " Prokarboksipolipeptidase " Prolipase " Tripsinogen
 
Group
PDC
 
Koenzim
AcCoA " CoA " CoQ10 " FAD " NAD+
 
Enzim
EC 1
.1
.1
Dehidrogenase alkohol
.3 HSD " .4 " .5 " .6 " .7 " .8 " .9 " .10 " .11 " .12 " .13 " .14 " .15 " .16 " .17 " .18 " .19 " .20 " .21 " .22 " .23 " .24 " .25 " .26 " .27 LDH " .146 11β-HSD " .196 15-PGDH
 
.2
 
.3
.1 " .2 " .4 GOX " .8 GLO
 
.2
.4
.1 PDH
 
.3
.5
.1 SCCR
SQR " QFR
 
.5
.5
.1 ETF-QO
 
.6
.5
.3 NADHD
 
.9
.3
.1 COX
 
.10
.2
.1 " .2 UCCR
 
.11
.1
.1 " .2 " .3 " .4 " .5 " .6 " .7 " .8 TPO
 
.13
 
.14
.13
.n7 2E1
 
.14
.1 2D6
 
.16
.3
 
EC 2
.3
.2
.1 " .2 GGT
 
.4
.1
 
.6
.1
.1 AST " .2 ALT
 
.7
.1-.4
.1
PI3K
.137 " .153 " .154
 
.2
 
.3
.1 " .2 CK
 
.4
 
.6
 
.7
DNA " Taq " Transkriptase " Telomerase
 
.10-.13
.10 TK
.1
 
.2
PTK-6
 
.11 STK
.1 Rsk " .2 PDK " .3 " .4 " .5 " .6 " .7 " .8 " .9 " .10 " .11 " .12 " .13 " .14 " .15 " .16 " DAPK " .18 " .19 " .20 " .21 " .22 CDK " .24 MAPK
 
.12
 
.13
F3 " Strepto
Glikosil
 
EC3
.1
.1
Lipase
.4 EL " .34 LPL " Fosfo
 
.2
 
.3
 
.2
.1
.1 PA " .2 " .3 " .4 " .5 " .6 " .7 " .8 " .9 " .10 " .11 " .12 " .13 " .14 " .15 " .16 " .17 " .18 " .19 " .20 " .21 " .22 α-gal " .23 β-gal " .166 HPA
 
.3
 
.4
.2
.1 CPA " .2 CPB " .3 CPS
 
.11-.19
.11-15
.11
 
.12
.2 CPA " .3 CPB " .7 CPN " .8 CPS " .11 ACP
 
.13
 
.14
 
.15
 
.16-.18
.16
 
.17
.1 CPA " .2 CPB " .3 CPN " .4 CPS " .6 ACP " .9 CPS " .21 PSMA
 
.18
 
.19
 
.21-.24
.21
FVII " FIX " FX " FXI " FXII " FD " PROC " Trombin
 
.22
 
.23
 
.24
 
.5
.1
 
.2
 
.3
ARG
 
.4
 
.5
 
.6
 
.7
 
EC 4
.1
.1
 
.2
 
.3
 
.2
 
.3
.1
 
.2
 
.4
 
.5
 
.6
Pektin
 
EC 5
 
EC 6
DNA
 
Helikase
 
Girase
 
Konvertase
 
Permease
ATPase " EEAT " FATP " GLUT " MCT " OATP " SGLT " UCP-1
Aldolase  · Fosfatase  · Laktase  · Nuklease  · Papain  · Rekonektin  · Renin  · Rennet  · Rubisco  · Selulase  · Sulfatase
 
Lihat pula : Asam amino " Darah " Hormon

Sumber :
m.andrafarm.com, wiki.gilland-ganesha.com, id.wikipedia.org, dsb.